by Patrick R. Coyle | Sep 13, 2026 | Patients + Profitability™
For most of my career I sat in rooms where the same question eventually surfaced. Are we optimizing for patients, or are we optimizing for the business? I asked it myself for years before I understood that the question was the problem. Patient outcomes and commercial...
by Patrick R. Coyle | Sep 11, 2026 | Patients + Profitability™
Approval day is the moment everyone celebrates, and it is the wrong milestone to organize a launch around. By the time it arrives, the people who will decide whether patients can actually get the therapy have already made up their minds about it. Market access is...
by Patrick R. Coyle | Sep 2, 2026 | Patients + Profitability™
CEOInsider has published a profile of this work: Following the Patient to Understand the Economics, written by Dennis Olympios. This post supplies the key. The journey the article follows is Patients + Profitability™, the transition points where patients disappear are...
by Patrick R. Coyle | Sep 2, 2026 | Patients + Profitability™
The short version: a pharmacy built on dispensing volume is easy to exploit and hard to defend, and enforcement actions and CMS quality measures already reward outcomes over counts. The pharmacy of the future will be paid for moving patients successfully through...
by Patrick R. Coyle | Aug 31, 2026 | Patients + Profitability™
Forecast accuracy is not the objective of a launch team. It is a precondition, and teams routinely mistake the two. The objective is knowing which decisions change when the numbers shift, and then acting on them. A forecast nobody acts on is a spreadsheet. It holds...
by Patrick R. Coyle | Aug 18, 2026 | Patients + Profitability™
The short version: revenue leakage declines because patient leakage declines first. Gross-to-Net is the financial record of every commercial decision that touched the patient journey, so the fastest way to improve it is to name the three worst friction points in that...
